Safer Opioid Supply Programs Evaluation in Toronto, Ontario
Canada continues to experience a fatal overdose epidemic resulting from the contamination of the unregulated drug supply. This has led to growing calls for piloting the provision of safer opioid supply programs (also known as safe supply), which are an extension of standard medication-assisted treatments such as methadone and buprenorphine/naloxone. In 2019, the CDPE published a commentary in the Canadian Journal of Public Health supporting the expansion of alternatives for pharmaceutical grade opioid options for people who use opioids. More recently, the CDPE participated in a scoping review on barriers to safer supply programs during COVID-19. Safer opioid supply regimens typically include an extended-release morphine sulfate and immediate release hydromorphone doses to offset or replace use of the contaminated unregulated drug supply and to thereby prevent overdose. An investment from Health Canada in September 2020 has scaled-up safer opioid supply programs.
Under the auspices of the Integrated Supervised Injection Services Evaluation, the CDPE is undertaking an evaluation of safer opioid supply programs in partnership with community healthcare agencies in downtown Toronto. This evaluation aims to uncover the impact of safer opioid supply programs by measuring health, social, and legal outcomes.
St. Michael’s Hospital Foundation
Moss Park Consumption and Treatment Service | Parkdale Queen West Community Health Centre | Regent Park Community Health Centre | South Riverdale Community Health Centre | Street Health | The Works at Toronto Public Health
Dr. Jeanette Bowles
The CDPE is leading a study to evaluate the impact of integrating supervised injection services within community healthcare agencies in Toronto, Ontario.View
The Ontario Integrated Supervised Injection Services Cohort Study of People Who Inject Drugs in Toronto, Canada (OiSIS-Toronto): Cohort Profile
The Ontario Integrated Supervised Injection Services cohort in Toronto, Canada (OiSIS-Toronto) is an open prospective cohort of people who inject drugs established to evaluate the impacts of supervised consumption services integrated within three community health agencies on health status and service use.View
Xylazine detected in unregulated opioids and drug administration equipment in Toronto, Canada: clinical and social implications
We report the first detection of the psychoactive veterinary compound xylazine in Toronto, the largest urban center in Canada, by the city’s drug checking service.View
This commentary explores the current state of policy and practice for diacetylmorphine and hydromorphone as opioid substitution options in Canada, outlines the rationale for rapid expansion of access, and highlights clinical and policy changes that must be undertaken or the death toll will continue to rise.View
A scoping review was conducted in order to identify key concepts, strategies and gaps in evidence with respect to the provision of safe supply during pandemics and other large-scale emergency conditions.View