This brief critical appraisal is intended to support interpretation and outline key limitations of a study published in the journal Addiction on March 10th, 2026 entitled “Healthcare utilization and mortality after overdose prevention site closure: A linked cohort analysis using segmented difference-in-differences time series”. It summarizes the study findings and also examines key methodological and interpretive limitations and contextual factors that should be taken into account to ensure appropriate application of the research findings. In particular, we summarize key limitations of the presented analyses with respect to the poor accounting for confounding service changes, potential model misspecifications, and undisclosed conflicts of interest.