Preventing Injecting by Modifying Existing Responses (PRIMER)
PRIMER (Preventing Injecting by Modifying Existing Responses) is a multi-country mixed methods study with the aim of identifying whether specific interventions and factors influence the risk that individuals begin injecting drugs.
PRIMER pools qualitative and quantitative data from cohorts of people who use drugs across seven different cities: Vancouver, Canada; San Diego, USA; Tijuana, Mexico; Paris, Marseille, Bordeaux and Strasbourg, France.
PRIMER is the largest study of injection drug use initiation (n = 3,850) and is the first to examine structural responses to preventing injection initiation. Findings can potentially improve the development and scaling up of interventions to reduce transitions into injection drug use.
National Institute on Drug Abuse | Canadian Institutes of Health Research | Government of Ontario: Ministry of Research, Innovation and Science
British Columbia Centre on Substance Use, Vancouver, Canada | Centre hospitalier régional et universitaire, Strasbourg, France | Institut national de la santé et de la recherche médicale, Marseille, France | Université de Bordeaux, Bordeaux, France | Université René Descartes, Paris, France | University of California, San Diego, USA | University of Xochicalco, Tijuana, Mexico
- Navigating social norms of injection initiation assistance during an overdose crisis: A qualitative study of the perspectives of people who inject drugs (PWID) in Vancouver, Canada.
- Prevalence and correlates of selling illicit cannabis among people who use drugs in Vancouver, Canada: A ten-year prospective cohort study.
- Identification of a Syndemic of Blood-Borne Disease Transmission and Injection Drug Use Initiation at the US-Mexico Border.
- Comparing risk environments for HIV among people who inject drugs from three cities in Northern Mexico.
- A fragmented code: The moral and structural context for providing assistance with injection drug use initiation in San Diego, USA.
- Injection Drug Use Trajectories among Migrant Populations: A Narrative Review.
- Increased non-fatal overdose risk associated with involuntary drug treatment in a longitudinal study with people who inject drugs.
- Do law enforcement interactions reduce the initiation of injection drug use? An investigation in three North American settings.
- Cross-border migration and initiation of others into drug injecting in Tijuana, Mexico.
- History of medication-assisted treatment and its association with initiating others into injection drug use in San Diego, CA.
- Preventing Injection Drug use Initiation: State of the Evidence and Opportunities for the Future.
- Non-injection Drug Use and Injection Initiation Assistance among People Who Inject Drugs in Tijuana, Mexico.
- Post-war prevention: Emerging frameworks to prevent drug use after the War on Drugs.
- The experience of initiating injection drug use and its social context: a qualitative systematic review and thematic synthesis.
- Differential experiences of Mexican policing by people who inject drugs residing in Tijuana and San Diego.
- How can we investigate the role of topiramate in the treatment of cocaine use disorder more thoroughly?
- The Spatial-Temporal Pattern of Policing Following a Drug Policy Reform: Triangulating Self-Reported Arrests With Official Crime Statistics.
- A socio-structural approach to preventing injection drug use initiation: rationale for the PRIMER study.
- Utilization of Google enterprise tools to georeference survey data among hard-to-reach groups: strategic application in international settings.
- Spatial patterns of arrests, police assault and addiction treatment center locations in Tijuana, Mexico.
- Topiramate for cocaine dependence: a systematic review and meta-analysis of randomized controlled trials.
- Risk of violence in drug rehabilitation centers: perceptions of people who inject drugs in Tijuana, Mexico.
- The effectiveness of compulsory drug treatment: A systematic review.
- Predictors of needle exchange program utilization during its implementation and expansion in Tijuana, Mexico.
A Fragmented Code: The Moral and Structural Context for Providing Assistance with Injection Drug Use Initiation in San Diego, USA
This study examines the social networks and structural contexts linked with assisting others in initiating injection drug use.View
This article examines the risk factors for injection drug use initiation that are associated with migration.View
Increased Non‐fatal Overdose Risk Associated with Involuntary Drug Treatment in a Longitudinal Study with People who Inject Drugs
This article examines the influence of involuntary drug treatment (IDT) on non‐fatal overdose among people who inject drugs (PWID).View
Do Law Enforcement Interactions Reduce the Initiation of Injection Drug Use? An Investigation in Three North American Settings
This article examines the influence that law enforcement interactions have on the reporting of people who inject drugs (PWID) of assisting others with injection initiation.View
This study examines the role of people who inject drugs (PWID) in facilitating the entry of others into injection initiation in settings characterized by cross-border migration that are associated with a unique risk environment.View
The Experience of Initiating Injection Drug Use and Its Social Context: A Qualitative Systematic Review and Thematic Synthesis
This study reviews the existing literature on the influence of socio-structural contexts on injection drug use initiation.View
History of Medication-assisted Treatment and its Association with Initiating Others into Injection Drug Use in San Diego, CA
This article examines whether a history of medication-assisted treatment for people who inject drugs (PWID) is associated with a reduced probability of providing injection initiation assistance.View
This article examines the evidence on the prevention of injection initiation to identify emerging intervention strategies and key barriers to effectively controlling the ongoing epidemicView
Non-injection Drug Use and Injection Initiation Assistance Among People Who Inject Drugs in Tijuana, Mexico
This article examines the risk factors among people who inject drugs (PWID) for providing assistance to other in injection initiation.View
This article explores current challenges to contain the opioid epidemic and calls for various treatments that could reduce the epidemic including the scaling up of medication-assisted treatment (MAT).View
A Socio-structural Approach to Preventing Injection Drug Use Initiation: Rationale for the PRIMER Study
This study explores the methodology employed in the PRIMER study.View
From Words to Action: Comparing the Disparities Between National Drug Policy and Local Implementation in Tijuana, Mexico and Vancouver, Canada
This article examines the discrepancies between federal policy and local responses to drug-related harms to understand the impact of national drug policies in shaping local responses to drug-related harms among people who use drugs (PWID).View